Anthropic's Claude Designs Protein Binders for 14 Targets
Anthropic reports Claude designed viable protein binders for 14 of 15 targets using expert prompts.
Anthropic announced that Claude used expert-written prompts to run protein binder design workflows and produced functional binders against 14 out of 15 biological targets. The company stated the effort replaced weeks or months of traditional expert work per target and released technical reports plus a video of nine experimentally confirmed binders. Replies note that specialized open-source models performed the core design steps rather than Claude alone and that the reported success rates match those of existing tools such as BindCraft for similar targets.
Many drugs work by binding to a specific target in the body and blocking or changing what it does. An important first step in the drug development process is designing a molecule that can bind tightly to its target. Traditionally, that's meant weeks or months of expert work per…
Reactions
33 postsAN 
Anthropic@AnthropicAIDesigning a binder is an easier process than designing a drug, but it’s a useful proxy. The typical success rate in the field today is between 10% and 15%. Between 22% and 35% of Claude's designs bound successfully, depending on the setup. Some of its strongest designs bound…
- likes: 1.1K
- replies: 14
- bookmarks: 101
- reposts: 41
AN Anthropic@AnthropicAIImportantly, protein binders are not drugs. Designing a high-affinity binder is just the first step in the process of developing a drug-like molecule. Even designing a drug itself is just one phase out of the many required to establish that a drug is safe and effective before…
- likes: 743
- replies: 7
- bookmarks: 33
- reposts: 18
AN Anthropic@AnthropicAIOne of our highest priorities remains launching an access program for scientists to use our most capable models. We expect to share more on this soon. Opus 5 remains our most capable model available for life science research.
- likes: 617
- replies: 10
- bookmarks: 28
- reposts: 12
AN Anthropic@AnthropicAIFor more on how Claude ran this experiment and the full results, see our blog:
- likes: 570
- replies: 10
- bookmarks: 126
- reposts: 21
AN Anthropic@AnthropicAIWe're also publishing a technical report: https://www-cdn.anthropic.com/30bf50e22a01388bb29bf077ee3f244531594b7a.pdf And open-sourcing our prompts and data here:
- likes: 447
- replies: 19
- bookmarks: 169
- reposts: 26
J⧉ j⧉nus@repligatewow.... claude invents new forms of pasta shaped like each letter of the word "ANTHROPIC"
- likes: 204
- replies: 12
- bookmarks: 12
- reposts: 7
